Principal Clinical Scientist

Columbus

**Principal Clinical Scientist (AI Training)** **About The Role** What if your career designing rigorous clinical trials and interpreting regulatory-grade data could directly shape how AI understands biomedical science? We're looking for a Principal Clinical Scientist to bring senior-level clinical expertise into the development of cutting-edge AI systems --- ensuring these models reason about clinical evidence the way the world's top regulatory scientists do. This is a fully remote, flexible contract role built for experienced clinical scientists who want to do meaningful work at the frontier of AI and biomedical research. * Organization: Alignerr * Type: Hourly Contract * Location: Remote * Commitment: 10--40 hours/week **What You'll Do** * Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training * Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards * Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance * Provide expert, structured feedback that shapes how AI models reason about clinical trial data, outcomes, and evidence * Work independently and asynchronously --- fully on your own schedule **Who You Are** * Senior-level experience designing clinical trial protocols intended for regulatory submission * Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent bodies * Strong command of clinical research methodology, biostatistics, or translational science * Rigorous, detail-oriented thinker who can translate complex clinical concepts into clear, structured feedback * Self-motivated and reliable when working independently without supervision **Nice to Have** * Prior experience with data annotation, data quality review, or AI evaluation workflows * Background in regulatory affairs, medical writing, or clinical operations * Familiarity with AI tools or machine learning applications in healthcare or life sciences * Experience contributing to multi-site or global clinical trials **Why Join Us** * Work directly on frontier AI systems making an impact in clinical and biomedical research * Fully remote and flexible --- work when and where it suits you * Freelance autonomy with the structure of meaningful, expert-level work * Influence how AI understands, evaluates, and reasons about real-world clinical evidence * Collaborate with world-leading AI research teams and labs * Potential for ongoing work and contract extension as new projects launch