Principal Clinical Scientist

Seattle

**Principal Clinical Scientist (AI Training)** **About The Role** What if your decades of clinical trial expertise could directly influence how AI understands and reasons about medical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research --- ensuring the clinical data powering next-generation AI systems meets the standards expected in real-world regulatory submissions. This is a fully remote, flexible contract role built for experienced clinical scientists who want to work at the frontier of AI and biomedical research --- on your schedule, without leaving your area of expertise. * Organization: Alignerr * Type: Hourly Contract * Location: Remote * Commitment: 10--40 hours/week **What You'll Do** * Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation * Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance * Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations * Provide structured expert feedback that directly improves how AI models reason about clinical trial data, endpoints, and outcomes * Help establish the standard for how clinical evidence is represented, evaluated, and used within advanced AI systems **Who You Are** * Senior clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission * Deep expertise interpreting clinical data for regulatory agencies such as the FDA, EMA, or equivalent bodies * Strong grounding in clinical research methodology, biostatistics, or translational science * Precise, detail-oriented communicator --- you can articulate complex scientific reasoning clearly and consistently * Self-directed and comfortable working independently on structured, task-based assignments **Nice to Have** * Prior experience with data annotation, data quality evaluation, or AI evaluation workflows * Background in pharmacovigilance, outcomes research, or evidence-based medicine * Familiarity with AI tools or clinical decision-support systems as an end user **Why Join Us** * Work directly on frontier AI systems shaping the future of clinical and biomedical research * Fully remote and flexible --- work on your own schedule from anywhere * Freelance autonomy with the structure of meaningful, high-impact work * Influence how AI understands, evaluates, and reasons about real-world clinical evidence * Collaborate with leading AI research teams and labs on cutting-edge projects * Potential for ongoing work and contract extension as new projects launch